Resources

Progress in science depends on new techniques, new discoveries and new ideas, probably in that order.

Stem cells, Protocols and Plasmids

  • Stem Cells:

    • JAX iPS cells (Link)

    • Coriell Institute Stem Cells (Link)

    • WiCell Research Institute (Link)

    • NYSCF repository (Link)

  • Protocols:

    • NIH Center for Alzheimer's and Related Dementias (Link)

    • Lentiviral transduction of iPSCs with sgRNAs and sgRNA libraries (Link)

    • iNeuron pre-differentiation & differentiation protocol V.2 (Link)

    • WTC11 iPSC Culture and Maintenance (Link)

    • Differentiation of iPSCs with the NGN2 construct into cortical neurons protocol (Link)

  • Plasmids:

    • Marius Wernig Lab Materials (Link)

    • Martin Kampmann Lab Materials (Link)

    • Michael Ward Lab Materials (Link)

    • iPSC Neurodegenerative Disease Initiative (iNDI) Lab Materials (Link)

Online Resources & Public Datasets:

  • The Myeloid Landscape 2 (Link)

  • Brain RNA-Seq (Link)

  • Microglia Gene List Enrichment Calculator (Link)

  • ABC Atlas (Link)

  • Human Cell Atlas Explorer (Link)

  • The Brain Immune Atlas (Link)

  • CZ CELLxGENE (Link)

  • Single Cell Portal (Link)

  • Panglao DB (Link)

  • The Mouse Brain Atlas (Link)

  • NeuroLipid Atlas (Link)

Conferences & Webinars:

  • European Microglia Webinar Series (Link)

  • Online Seminars:

    • Marius Wernig: Next generation cell therapies for the brain @ NHGRI DIR Seminar Series (Link)

    • Beth Stevens #1: Microglia States in Health and Disease (Link)

    • Beth Stevens #2: How Microglia Sculpt Brain Circuitry in Health and Disease (Link)

    • Beth Stevens: Redefining Microglia States and Function in Alzheimer’s Disease (Link)

    • Bess Frost: Transposable Element Activation in Neurodegenerative Tauopathy: From Bench to Bedside (Link)

    • David Holtzman: Sleep & the Pathophysiology of Alzheimer's Disease (Link)

    • Ben Barres: What do reactive astrocytes do? (Link)

    • Bo Peng: Microglia replacement: from bench to clinical therapy (Link)

    • Marco Prinz: The myeloid side of brain (Link)

    • Martin Kampmann: Multiplexing with CRISPR Screens (Link)

    • Jennifer Doudna: CRISPR-Cas9: From Biology to Transformative Technology (Link)

    • Anna Molofsky: Regulation of microglial function by cytokines (Link)

    • Anne Schaefer: Negative feedback control of neuronal activity by microglia (Link)